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Viagra is the brand name for sildenafil, one of the best-known drugs for the medical treatment of erectile dysfunction. But the invention of this "blue pill" was an unforeseen and fortuitous event.

In the 1980s, Sildenafil was originally developed to treat hypertension and stenocardia. During clinical trials, researchers discovered that the drug had a side effect in the form of a strong erection.

Representatives of the Pfizer company realized that treating erectile dysfunction with oral therapy was an unmet medical need. In 1998, the FDA approved Viagra and the drug arrived in the Netherlands. Viagra is a safe drug and this safety combined with ease of use contributes to its popularity.

Do you know that about 28% of men face the problem of sexual dysfunction? Many men experience this at some point in their lives, and the reasons may be physical or psychological. Erectile dysfunction (impotence) is a condition in which a man cannot get or maintain an erection. This has a negative effect on sexual life, as well as on self-esteem and self-confidence. Moreover, erectile dysfunction can be an indicator of other serious diseases, such as heart disease, diabetes, etc. Generic Viagra is a medication that can address erectile dysfunction and prevent the related problems.

As drug prices continue to rise (including Pfizer's recent 10% increase), generics are becoming an excellent alternative. In 2018, new manufacturers of generic Viagra entered the market, which meant even more savings for men. Onlinepharma24 is an online pharmacy where you can buy generic sildenafil online without a prescription. This allows us to serve a wider customer segment around the world. We only supply medications approved by drug regulatory agencies such as the FDA and WHO.

Short story

March 27, 1998 is the date Viagra met the world. Before this date, men with erectile dysfunction had very few treatment options. Before the 1980s, it was believed that problems getting an erection were due to anxiety. This was why psychotherapy became the main treatment option. A few years later, scientists moved away from this theory and focused on treating the physical causes of the disease.

Invasive treatments, however, had serious side effects. Administration of drugs into the penis gave a powerful effect, but also often led to priapism (an erection lasting longer than 4 hours).

Viagra was the first oral medication that could safely and effectively address the physical causes of erectile dysfunction.

How does Viagra work?

After ingestion, sildenafil enters the stomach and is absorbed into the blood. Once in the blood, the active ingredient inhibits the action of the enzyme phosphodiesterase 5, the sole cause that restricts blood flow to the penis.

Limiting PDE 5 activity leads to an increase in the levels of cyclic guanosine monophosphate (cGMP) and nitric oxide (NO), which are powerful vasodilators. As a result, blood vessels dilate and blood flow to the penis increases, allowing a man to achieve an erection at the moment of sexual arousal.

How the erection occurs

Let's look at how erection occurs. Nitric oxide (NO) is a signaling molecule that dilates blood vessels and is responsible for changing blood pressure. This compound is released into the erectile tissue of the penis when the man becomes aroused. Viagra causes an erection in response to sexual stimulation, increasing blood flow to the penis.

As noted above, stenocardia is caused by a restricted blood supply to the heart muscle. Similarly, it is difficult for a man to get an erection if the blood supply to the penis is restricted. Now it is easier to understand why the drug designed to relieve chest pain ultimately helps men get an erection. The launch of a new version of Generic Viagra, which does not require a prescription, has helped thousands of men try an erection pill for the first time.

How do you take Viagra?

It is recommended that Viagra be taken about 1 hour before scheduled sexual intercourse. The dosage can be adjusted according to the doctor's recommendations.

The standard recommended dose of Viagra is 100 mg, although it can be increased to 200 mg or decreased to 25 mg, depending on effectiveness and side effects. You should start with a lower dose and then adjust it according to the body's response.

How long does the effect of Viagra last?

Viagra begins to show its effect within 30-60 minutes of use. The effect of this drug lasts for 4-5 hours.

Viagra's duration of action will increase in cases of liver or kidney disease because the breakdown and release of sildenafil from the body slows down due to impaired liver and kidney function. In men older than 65 years, the duration of action also tends to increase. In these cases, a dose reduction is usually recommended. Do not consume fatty foods, as well as grapefruit or grapefruit juice, as they delay the onset of the effect.

Dosage

Viagra is available in dosages: 25 mg, 50 mg, 100 mg and 200 mg.

The effect of Viagra is enhanced with increasing dosage. The standard recommended dose for most men is 100 mg. If this dose is not effective, try 200 mg. If 100 mg causes side effects, reduce the dose to 50 mg.

An initial dose of 25 mg is recommended for elderly patients and patients with severe renal and/or hepatic impairment. It is important that you choose the correct dose. Check with your pharmacist or contact our customer service department.

What is the difference between Viagra and Generic Viagra?

Although they may vary in color and pill form, both drugs have the same active ingredient, sildenafil. Generic Viagra will work just as well as original if the medication is purchased from a licensed pharmacy. So why is there a price difference?

Viagra is a patented drug. But last year the patent expired and other companies were able to produce and sell generic Viagra. Because they didn't have to spend money on research and advertising, you can buy generic Viagra at a much lower price.

Viagra generic drugs include Fildena, Aurogra, Silagra, Sildalis, Nizagra and Caverta. These drugs are manufactured by several pharmaceutical companies, including Actavis, Mylan, Sandoz and Cipla.

Is there an alternative to Viagra?

Viagra is effective in 82% of cases. Don't worry if you don't make the lucky list. There are many other alternatives that are similar in effect. We recommend that you try one of the other PDE-5 inhibitors available in Spain. These are Cialis, Levitra, Spedra.

Where can I buy Viagra in the Netherlands?

Having a happy and healthy sex life can be a problem. Remember that improving daily life by reducing stress is a great way to reduce the risk of erectile dysfunction. For those who need some extra help, Viagra pills can be a good start.

Our online pharmacy helps you get Viagra safely and legally. Customers who have used Viagra from onlinepharma24.co.uk rated their experience as 'excellent'. We try to offer quality service at a good price. If you would like to seek advice or more information about the products we offer, please contact our support team.

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Medical interactions

There are a number of medications that interact with sildenafil. A complete list can be found in the patient information sheet. You can view the main drug interactions here:

  • Recreational drugs such as poppers;
  • Alpha blockers;
  • Antibiotics such as erythromycin;
  • Antifungals such as itraconazole;
  • Antiviral drugs, such as those used to treat HIV infection;
  • Dapoxetine (Priligy, used to treat premature ejaculation);
  • Nitrates and other drugs used to treat pulmonary arterial hypertension;
  • Cimetidine (for the treatment of peptic ulcers).

Do not use Viagra if you have used any of the above medications in the past 60 days without first consulting your doctor.

Safety measures

  • Seek immediate medical attention if you have difficulty breathing, chest pain or prolonged erection;
  • Consult your doctor before changing the dose;
  • Avoid alcohol, tobacco and fatty foods when receiving this medicine.

Side effects

Viagra is generally well tolerated, but side effects may include headache, dizziness, blurred vision, nausea and upset stomach.

Such effects usually disappear within a short time. If you experience a prolonged or painful erection (more than 4 hours), you should consult your doctor immediately.

Only 3.1% of patients stop using Viagra because of unpleasant side effects.